4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-o ne is also used in the preparation of prodrugs of ampicillin.
4-Chloromethyl-5-methyl-1,3-dioxol-2-one is used as a pharmaceutical intermediate, olmesartan intermediate, olmesartan medoxoside side chain DMDO-CL.
11 Carbonyldiimidazole is a peptide coupling reagent, it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles subsequent reaction with amines to form amides goes smoothly.
Dicydohexyl carbodiimide is used in peptide chemistry as a coupling reagent. It is both an irritant and a sensitizer, and caused contact dermatitis in pharmacists and chemists.N N-Dicyclohexylcarbodiimide is a carbodiimide used to couple amino acids during peptide synthesis. N N Dicyclohexylcarbodiimide is used as a dehydrating agent for the preparation of amides, ketones , nitriles as well as in the inversion and esterification of secondary alcohols.
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